News from Wednesday, September 20, 2023
Articles
Two Pediatric Sinusitis Antibiotics Found Equally Effective
(9/29, Chris Dall, MA, CIDRAP) reports “The results of a large observational study in children show no difference in treatment failure rates between the two most commonly prescribed antibiotics for pediatric acute sinusitis, researchers reported today in JAMA. Overall, treatment failure for sinus infections was rare in children treated with amoxicillin or amoxicillin-clavulanate. But the latter was associated with more adverse events...” Full
Value-Based Payments Are Making it Harder to See Your Primary Care Doctor on Short Notice
(9/20, Jeffrey Millstein, STAT) comments “...Physician leaders must push for value-based incentives that better align with patient needs and goals, and allow primary care clinicians the autonomy to balance routine and acute/subacute visits to meet practice demands. For instance, limiting yearly comprehensive visits to patients in the highest risk subgroups should meet the metric threshold.” Full
Shutdown Threat Clouds Start of Biden Drug-Pricing Negotiations
(9/20, Alex Ruoff, Bloomberg Law) reports “...A potential government shutdown at the end of the month risks complicating the Biden administration's top health priorities, just as drugmakers are supposed to report data for pricing negotiations and states are pushing people off Medicaid rolls...A shutdown would bump up against an Oct. 2 deadline for some drugmakers to report a slew of data to Medicare as part of how the agency will eventually determine new prices for medicines selected for negotiation.” Full
Press Releases
PCORnet® Leaders Hit The Road To Share How The Network Works And Why Researchers Should Use It To Power Their Next Study
(9/20, PCORnet Press Release) “Why and how should you use PCORnet®? That’s the question PCORnet leaders sought to answer when they recently presented at an adjunct event for AcademyHealth’s 2023 Annual Research Meeting (ARM) and at a half-day virtual convening held by NORC in collaboration with PCORI. Both events were a chance to showcase the uniqueness of PCORnet, which was developed in 2014 with funding from PCORI as a national resource for all.” Full
Journals
Addressing Missing Data in the Estimation of Time-Varying Treatments in Comparative Effectiveness Research
Juan Segura-Buisan, Clemence Leyrat, Manuel Gomes
September 19, 2023, Statistics in Medicine
Treatment Failure and Adverse Events After Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis
Timothy J. Savage, MD, MPH, MSc, et al.
September 19, 2023, JAMA
Network Meta-Analysis of Adjuvant Treatments for Patients with Hepatocellular Carcinoma after Curative Resection
Yanyan Ye, et al.
September 20, 2023, BMC Gastroenterology
Challenges of Calculating Cost-Effectiveness Thresholds – Authors' Reply
Andres Pichon-Riviere, et al.
October 2023, The Lancet Global Health