News from Friday, October 4, 2024
Articles
Apalutamide vs Enzalutamide for mCSPC Offers Better Survival, Real-World Data Show
(10/4, Natasha Persaud, Renal & Urology News) reports “Apalutamide is associated with better 24-month overall survival compared with enzalutamide among real-world patients with metastatic castration-sensitive prostate cancer (mCSPC), investigators reported in a late-breaking abstract at the 6th European Congress of Oncology Pharmacy in Lisbon, Portugal.” Full
FDA: Integrated Clinical Trials Most Appropriate For Postmarket Drugs
(10/4, Jessica Karins, Inside Health Policy) reports “...‘There has been increasing interest in the use of real-world data acquired during routine clinical practice to support drug development,’ the guidance says. The final guidance is part of FDA’s efforts to boost use of real-world evidence. It is intended to support randomized controlled trials with streamlined protocols focusing on collection of essential safety data, which allows the integration of the trial into routine clinical practice.” Subscription Required
Virtual Palliative Care Outcomes Similar to In-Person, Study Finds
(10/4, Olivia Dimmer, Northwestern Medicine) reports “Patients receiving palliative care via telehealth reported similar quality-of-life scores compared to those who had in-person care, according to a multicenter clinical trial recently published in JAMA...The study was supported by National Institutes of Health grant R-1609-35995, with additional funding from the Patient-Centered Outcomes Research Institute.” Full
Press Releases
Jefferson Health Awarded $2.4 Million in PCORI Funding
(10/4, Thomas Jefferson University Press Release) “Jefferson Health has been awarded $2.4 million by the Patient-Centered Outcomes Research Institute to implement evidence-based patient education and coaching programs for weight loss across Jefferson Primary Care.” Full
Mercy Awarded Nearly $3 Million for Obesity Funding
(10/3, Mercy Press Release) “Mercy received a nearly $3 million funding award from the Patient-Centered Outcomes Research Institute through its Health Systems Implementation Initiative (HSII) to implement intensive lifestyle treatment programs for weight loss within primary care settings, one of only six health systems in the United States to receive funding for the project.” Full
Predicting Patient Outcomes Via Machine Learning Models
(10/3, Stony Brook University News Release) “...The research is supported by a $1.05 million grant from the Patient-Centered Outcomes Research Institute...[Fusheng Wang, PhD’s] research on using machine learning to predict patient risk was the basis for the award. He focuses on creating models to predict how likely patients are to develop opioid use disorder and opioid overdose.” Full
Journals
Telehealth vs In-Person Early Palliative Care for Patients With Advanced Lung Cancer: A Multisite Randomized Clinical Trial
Joseph A. Greer, PhD; Jennifer S. Temel, MD; Areej El-Jawahri, MD; et al
September 11, 2024, JAMA
Public Sector Replacement of Privately Funded Pharmaceutical R&D: Cost and Efficiency Considerations
David Proudman, et al.
October 3, 2024, Journal of Medical Economics
Comparative Effectiveness of Baricitinib Versus Tocilizumab in Hospitalized Patients With COVID-19: A Retrospective Cohort Study of the National Covid Collaborative
Asad E Patanwala, et al.
October 4, 2024, Critical Care Medicine