NPC Seeking Research Proposals on Individual Treatment Effects

The Patient-Centered Outcomes Research Institute isn’t the only organization seeking research proposals—the National Pharmaceutical Council (NPC) is, too!

Now through September 30, NPC is accepting proposals that identify and address patient heterogeneity of treatment effect (HTE), and how HTE should be considered to achieve better health outcomes for both the individual patient and the population. NPC has coordinated some HTE research projects focused upon a small number of conditions, including schizophrenia and depression, but we are looking for proposals to help identify and understand HTE in additional compelling clinical areas. (Click here to view the detailed description of the proposal.)

Interested in applying? Here’s what you need to know about submitting a proposal:

Proposals for this project should

1. Identify health condition case examples for which considerable HTE exists
2. Develop a strategy to analyze the variable treatment responses associated with care of this health condition and the best treatment strategies for individual patient-centered care
3. Analyze the implications for payers and providers of basing all treatment decisions on a determined “average” patient response, and
4. Potentially identify and discuss research and policy options for the consideration of HTE in treatment decisions.

Proposed research concepts also should provide an explanation of all project objectives, an overview of the proposed approach to the project, and a description of the project’s overall value. Submissions will be evaluated based upon a combination of factors, including: the potential impact of the research; availability of data and content; project duration; certainty of outcome; cost; how the research can be presented; and to what extent the research is important to key audiences. While budget and timeframe are project specific, lower cost projects between $50,000-$150,000 and with shorter term (<6 months, or 6-12 months) will be given higher priority in review.

Submissions should be made to the attention of Adam Lustig, NPC research associate, and should generally be between 3-5 pages.