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The National Pharmaceutical Council (NPC) is a health policy research organization dedicated to the advancement of good evidence and science, and to fostering an environment in the United States that supports medical innovation.

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Say GRACE! Principles for Observational Studies

Research critics often point to methodological weaknesses inherent in observational studies, coupled with the lack of standard principles to assess their quality, as practical limitations to their…

RCTs vs. Observational Studies?

Randomized controlled trials (RCTs) can be the best way to answer a particular health care question, but they don’t reflect the real world, explains Dr. Robert Dubois, chief science officer at the…

Why Observational Studies Matter

Next week, the Institute of Medicine (IOM), in conjunction with the Patient-Centered Outcomes Research Institute (PCORI), will be holding a two-day workshop on the use of observational studies in a…